Description

1H-Indole, 3-(3-Azetidinyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D. The product, CAS NO 1368911-80-1, is supplied under stringent quality control to ensure batch-to-batch consistency for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged indole-azetidine scaffold.
• Process Chemistry Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Synthesis: Utilized for creating chemical probes and labeled compounds for biological assay development and diagnostic research.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and bioorganic synthesis.

Basic Information

Product Name	1H-Indole, 3-(3-Azetidinyl)-
CAS No.	1368911-80-1
Molecular Formula	C11H12N2
Molecular Weight	172.23 g/mol
Synonyms	3-(Azetidin-3-yl)-1H-indole; 3-(3-Azetidinyl)indole; 1H-Indole-3-azetidine; Azetidin-3-yl-1H-indole; 3-Azetidin-3-ylindole; Indol-3-ylazetidine; (1H-Indol-3-yl)azetidine
EINECS	Contact for details

Quality Control

Our 1H-Indole, 3-(3-Azetidinyl)- is manufactured under a quality management system to ensure high purity and reliability for research and development applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.