Description

5-Fluoro-8-Methoxy-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry for developing new therapeutic agents. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for its unique fluorinated and methoxylated tetrahydroisoquinoline scaffold.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new pesticides and herbicides with enhanced activity.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, dyes, and complex organic compounds.
• Academic & R&D Laboratories: Utilized in organic synthesis research and methodological development due to its reactive functional groups.

Basic Information

Product Name	5-Fluoro-8-Methoxy-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1368777-04-1
Molecular Formula	C₁₀H₁₂FNO
Molecular Weight	181.21 g/mol
Synonyms	8-Methoxy-5-fluoro-1,2,3,4-tetrahydroisoquinoline; 5-Fluoro-8-methoxy-1,2,3,4-tetrahydro-isoquinoline; 1,2,3,4-Tetrahydro-5-fluoro-8-methoxyisoquinoline; 5-Fluoro-8-methoxy-THIQ; F-Methoxy-THIQ
EINECS	Contact for details

Quality Control

Our 5-Fluoro-8-Methoxy-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.