Description

1-Bromo-6-Nitro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated nitro-isoquinoline structure. This compound is of significant value for its role as a versatile building block in medicinal chemistry and drug discovery research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the isoquinoline scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging its reactive bromo and nitro functional groups for further chemical modifications.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, or photoactive materials in advanced material applications.
• Academic & Contract Research: Essential for academic institutions and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and method development.
• Chemical Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	1-Bromo-6-Nitro-Isoquinoline
CAS No.	1368380-95-3
Molecular Formula	C9H5BrN2O2
Molecular Weight	253.06 g/mol
Synonyms	6-Nitro-1-bromoisoquinoline; 1-Bromo-6-nitroisoquinoline; Isoquinoline, 1-bromo-6-nitro-; 1368380-95-3; 1-Bromo-6-nitro-isoquinoline; 1-Brom-6-nitro-isochinolin (German); 1-ブロモ-6-ニトロイソキノリン (Japanese)
EINECS	Contact for details

Quality Control

Our 1-Bromo-6-Nitro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.