Description

Isoquinoline, 5-Bromo-1-Chloro-6-Fluoro- is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures with tailored electronic and steric properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the halogenated isoquinoline core.
• Material Science Precursor: Acts as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functionalization in medicinal chemistry.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and for contract research organizations (CROs) supporting drug discovery programs.

Basic Information

Product Name	Isoquinoline, 5-Bromo-1-Chloro-6-Fluoro-
CAS No.	1368066-64-1
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	5-Bromo-1-chloro-6-fluoroisoquinoline; 1-Chloro-5-bromo-6-fluoroisoquinoline; 6-Fluoro-5-bromo-1-chloroisoquinoline; 5-Bromo-6-fluoro-1-chloroisoquinoline; Isoquinoline, 1-chloro-5-bromo-6-fluoro-; 1368066-64-1; 5-Br-1-Cl-6-F-isoquinoline
EINECS	Contact for details

Quality Control

Every batch of Isoquinoline, 5-Bromo-1-Chloro-6-Fluoro- is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.