Description

8-Chloroisoquinolin-1(2H)-One is a versatile and high-value heterocyclic building block, specifically a chlorinated isoquinolinone derivative. This compound is of significant interest for its role as a key synthetic intermediate in advanced organic chemistry and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinases, enzymes, and various central nervous system (CNS) receptors.
• Agrochemical Research: Serves as a building block for developing new active ingredients with herbicidal, fungicidal, or insecticidal properties.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular scaffold or probe in the study of biological pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	8-Chloroisoquinolin-1(2H)-One
CAS No.	1368031-04-2
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	8-Chloro-1H-isoquinolin-1-one; 8-Chloro-1,2-dihydroisoquinolin-1-one; 8-Chloroisoquinolin-1-ol; 1(2H)-Isoquinolinone, 8-chloro-; 1368031-04-2
EINECS	Contact for details

Quality Control

Every batch of 8-Chloroisoquinolin-1(2H)-One is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity (typically ≥95% to ≥98% by HPLC), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.