Description

6-Fluoro-1H-Indol-5-Amine is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which is essential for constructing complex pharmacophores and functional materials. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Biochemical Probe Development: Employed in medicinal chemistry to create fluorescent probes or labeled compounds for biological assays and imaging.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploratory synthetic chemistry projects.
• Fine Chemical Production: Acts as a starting material for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	6-Fluoro-1H-Indol-5-Amine
CAS No.	1367958-40-4
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	5-Amino-6-fluoro-1H-indole; 6-Fluoro-1H-indol-5-ylamine; 6-Fluoro-5-aminoindole; 1H-Indol-5-amine, 6-fluoro-; 6-Fluoroindol-5-amine; 5-Amino-6-fluoroindole; 1367958-40-4
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1H-Indol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP-grade requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.