Description

5-Bromo-6-Fluoro-1,2-Dihydroisoquinolin-1-One is a high-purity, advanced pharmaceutical intermediate with significant value in modern synthetic chemistry. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated isoquinolinone structure.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial R&D.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process scale-up services for client projects.

Basic Information

Product Name	5-Bromo-6-Fluoro-1,2-Dihydroisoquinolin-1-One
CAS No.	1367774-38-6
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	5-Bromo-6-fluoro-1,2-dihydroisoquinolin-1-one; 5-Bromo-6-fluoro-3,4-dihydro-1H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 5-bromo-6-fluoro-1,2-dihydro-; 1367774-38-6; 5-Br-6-F-DHIQ; 5-Bromo-6-fluoro-1,2-dihydroisoquinolone
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-6-Fluoro-1,2-Dihydroisoquinolin-1-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.