Description

4-(Aminomethyl)-1-Methyl-5,6,7,8-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its functionalized tetrahydroisoquinoline core. This compound matters as a critical building block for medicinal chemistry research and the synthesis of complex bioactive molecules, offering a versatile scaffold for drug discovery. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers engaged in developing new therapeutic agents, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those with tetrahydroisoquinoline-based pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides that require complex amine-functionalized heterocycles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Functionalized to create molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Production: A building block for the custom synthesis of specialty chemicals and high-value performance materials.

Basic Information

Product Name	4-(Aminomethyl)-1-Methyl-5,6,7,8-Tetrahydroisoquinoline
CAS No.	1365939-72-5
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	1-Methyl-4-(aminomethyl)-5,6,7,8-tetrahydroisoquinoline; 4-(Aminomethyl)-1-methyl-1,2,3,4-tetrahydroisoquinoline; 1-Methyl-4-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline; 4-(Aminomethyl)-1-methyl-5,6,7,8-tetrahydroisoquinoline; 1-Methyl-4-aminomethyltetrahydroisoquinoline; 4-Aminomethyl-1-methyltetrahydroisoquinoline; Tetrahydroisoquinoline derivative 1365939-72-5
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-1-Methyl-5,6,7,8-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.