Description

(3-Trifluoromethylphenyl)Dimethylphosphonoacetate is a high-value organophosphorus building block characterized by its trifluoromethylphenyl and phosphonoacetate functional groups. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where it introduces key structural motifs. It is primarily needed by R&D chemists and process development scientists in the fine chemical, crop protection, and pharmaceutical industries seeking to develop novel active ingredients.

Application

• Agrochemical Intermediate: A key synthon for the development of novel herbicides, insecticides, and fungicides, leveraging the biological activity of the trifluoromethyl and phosphonate groups.
• Pharmaceutical Research: Serves as a versatile building block in medicinal chemistry for creating potential drug candidates, particularly in protease inhibitor and enzyme modulator programs.
• Ligand Synthesis: Used in the preparation of specialized phosphonate-based ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of functionalized monomers or additives for advanced polymeric materials.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and mechanism.

Basic Information

Product Name	(3-Trifluoromethylphenyl)Dimethylphosphonoacetate
CAS No.	1365808-85-0
Molecular Formula	C11H12F3O4P
Molecular Weight	296.18 g/mol
Synonyms	Dimethyl (3-(trifluoromethyl)phenyl)phosphonoacetate; Phosphonoacetic acid, P-[3-(trifluoromethyl)phenyl]-, dimethyl ester; (3-Trifluoromethylphenyl)dimethyl phosphonoacetate; Dimethyl [(3-trifluoromethyl)phenyl]phosphonoacetate; m-Trifluoromethylphenyl dimethylphosphonoacetate; 3-Trifluoromethylphenyl dimethyl phosphonoacetate; (m-Trifluoromethylphenyl)dimethylphosphonoacetate
EINECS	Contact for details

Quality Control

Our (3-Trifluoromethylphenyl)Dimethylphosphonoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.