Description

tert-Butyl 3-Amino-6-Cyclopropyl-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of innovative therapeutic agents, particularly within oncology and other specialized drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in research and development for constructing novel pyrrolopyrazole-based molecular scaffolds with potential biological activity.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Biochemical Research: May serve as a tool compound or a ligand in biochemical assays and proteomics studies.

Basic Information

Product Name	tert-Butyl 3-Amino-6-Cyclopropyl-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxylate
CAS No.	1363404-97-0
Molecular Formula	C13H20N4O2
Molecular Weight	264.33 g/mol
Synonyms	1H-Pyrrolo[3,4-c]pyrazole-5(4H,6H)-carboxylic acid, 3-amino-6-cyclopropyl-1,4,5,6-tetrahydro-, 1,1-dimethylethyl ester; tert-Butyl 3-amino-6-cyclopropyl-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxylate; 6-Cyclopropyl-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester 3-amine; BOC-protected 3-amino-6-cyclopropyl pyrrolopyrazole; 1363404-97-0; tert-Butyl 3-amino-6-cyclopropyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-6-Cyclopropyl-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.