Description

4-Chloro-Thiazole-2-Carbonitrile is a high-value heterocyclic building block characterized by its reactive chloro and nitrile functional groups. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key precursor. It is primarily sought after by research chemists and process development scientists working on novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, antibacterial, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiazole core for bioactivity.
• Material Science Research: Serves as a building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and click chemistry reagents for biological studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-Thiazole-2-Carbonitrile
CAS No.	1363383-13-4
Molecular Formula	C4HClN2S
Molecular Weight	144.58 g/mol
Synonyms	2-Cyano-4-chlorothiazole; 4-Chloro-2-thiazolecarbonitrile; 4-Chloro-2-cyanothiazole; 4-Chlorothiazole-2-carbonitrile; 2-Thiazolecarbonitrile, 4-chloro-; Thiazole, 4-chloro-2-cyano-; 1363383-13-4
EINECS	Contact for details

Quality Control

Our 4-Chloro-Thiazole-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.