Description

1-(5-Chloro-Thiophen-3-Yl)Ethanol is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its functionalized thiophene core, which is crucial for constructing complex molecules with specific electronic and steric properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Active Ingredient Precursor: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorothiophene moiety.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of conjugated polymers and organic semiconductors for electronic applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-purity chiral intermediates.

Basic Information

Product Name	1-(5-Chloro-Thiophen-3-Yl)Ethanol
CAS No.	1363383-08-7
Molecular Formula	C6H7ClOS
Molecular Weight	162.63 g/mol
Synonyms	1-(5-Chlorothiophen-3-yl)ethanol; 1-(5-Chloro-3-thienyl)ethanol; 5-Chloro-3-thiopheneethanol; (5-Chloro-3-thienyl)methanol (related); α-Methyl-5-chloro-3-thiophenemethanol; 1363383-08-7; 3-Thiopheneethanol, 5-chloro-
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-Thiophen-3-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.