Description

1-(5-Chloro-Thiophen-3-Yl)Ethylamine is a high-purity, versatile organic building block featuring a chlorinated thiophene core with an ethylamine side chain. This compound is essential for advanced chemical synthesis, offering a unique heterocyclic scaffold for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Research: Serves as a crucial precursor in the synthesis of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene moiety.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Ligand Synthesis: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry for studying biological processes.
• Custom Synthesis & Scale-up: A fundamental building block for contract research organizations (CROs) and custom synthesis manufacturers for client-specific projects.

Basic Information

Product Name	1-(5-Chloro-Thiophen-3-Yl)Ethylamine
CAS No.	1363381-05-8
Molecular Formula	C6H8ClNS
Molecular Weight	161.65 g/mol
Synonyms	1-(5-Chlorothiophen-3-yl)ethan-1-amine; 1-(5-Chloro-3-thienyl)ethylamine; 5-Chloro-3-thiopheneethanamine; α-Methyl-5-chloro-3-thiophenemethylamine; (5-Chloro-3-thienyl)ethylamine; 1-(5-Chloro-thiophen-3-yl)-ethylamine; 1363381-05-8
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-Thiophen-3-Yl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.