Description

5,6-Dihydro-4H-Thieno[3,4-C]Pyrrole Hydrobromide is a high-purity, advanced pharmaceutical intermediate with the CAS number 1363166-04-4. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique fused-ring structure that enables the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the construction of the core pharmacophore for potential new chemical entities (NCEs).
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	5,6-Dihydro-4H-Thieno[3,4-C]Pyrrole Hydrobromide
CAS No.	1363166-04-4
Molecular Formula	C6H8BrNS
Molecular Weight	206.10 g/mol
Synonyms	4H-Thieno[3,4-c]pyrrole, 5,6-dihydro-, hydrobromide; Thieno[3,4-c]pyrrole, 5,6-dihydro-4H-, hydrobromide; 5,6-Dihydro-4H-thieno[3,4-c]pyrrole HBr; 1363166-04-4; 5,6-Dihydro-4H-thieno[3,4-c]pyrrole hydrobromide salt
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-4H-Thieno[3,4-C]Pyrrole Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and pre-clinical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.