Description

1-Bromo-4-Iodo-2-Methoxy-5-Nitro-Benzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen and nitro functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogenated nitrobenzene core.
• Material Science: Serves as a monomer or precursor for creating advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Heck) due to the presence of both bromo and iodo leaving groups, allowing for selective functionalization.
• Chemical Research: Employed in academic and industrial R&D for methodological studies in organic synthesis and as a standard for analytical method development.
• Dye and Pigment Intermediate: Used in the synthesis of complex, high-performance dyes and pigments.

Basic Information

Product Name	1-Bromo-4-Iodo-2-Methoxy-5-Nitro-Benzene
CAS No.	1361021-39-7
Molecular Formula	C7H5BrINO3
Molecular Weight	357.93 g/mol
Synonyms	4-Bromo-1-Iodo-2-Methoxy-5-Nitrobenzene; 2-Methoxy-5-Nitro-1,4-Dibromobenzene (Iodo Analog); 1-Bromo-4-iodo-2-methoxy-5-nitrobenzene; 5-Nitro-2-methoxy-1,4-dihalobenzene (Br, I); Benzene, 1-bromo-4-iodo-2-methoxy-5-nitro-; 2-Methoxy-5-nitro-1-bromo-4-iodobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Iodo-2-Methoxy-5-Nitro-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.