Description

7-Bromo-1H-Indazole-3-Carbonitrile is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and targeted cancer therapies.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive bromine and nitrile sites.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Material Science: Acts as a building block for creating specialized polymers and organic electronic materials.
• Chemical Biology: Utilized in the design and synthesis of chemical probes for studying biological pathways and protein functions.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	7-Bromo-1H-Indazole-3-Carbonitrile
CAS No.	1360941-93-0
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	7-Bromo-1H-indazole-3-carbonitrile; 3-Cyano-7-bromo-1H-indazole; 7-Bromoindazole-3-carbonitrile; 1H-Indazole-3-carbonitrile, 7-bromo-; 1360941-93-0; 7-Bromo-1H-indazol-3-yl cyanide
EINECS	Contact for details

Quality Control

Our 7-Bromo-1H-Indazole-3-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.