Description

5-Bromo-6-Fluoro-1H-Indazole-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique indazole core, which serves as a privileged scaffold in medicinal chemistry for constructing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in the study of biological pathways and protein interactions.
• Material Science Research: Serves as a precursor for synthesizing advanced organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Bromo-6-Fluoro-1H-Indazole-3-Carboxylic Acid
CAS No.	1360928-47-7
Molecular Formula	C8H4BrFN2O2
Molecular Weight	259.03 g/mol
Synonyms	5-Bromo-6-fluoro-1H-indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 5-bromo-6-fluoro-; 1360928-47-7; 5-Bromo-6-fluoroindazole-3-carboxylic acid; 6-Fluoro-5-bromo-1H-indazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoro-1H-Indazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.