Description

5-Methyl-1H-Indazole-4-Carboxylic Acid is a high-purity, versatile indazole-based carboxylic acid building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical candidates, particularly in kinase inhibitor and oncology research. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indazole core.
• Material Science: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes and bioconjugates for target identification and validation.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis in medicinal chemistry.

Basic Information

Product Name	5-Methyl-1H-Indazole-4-Carboxylic Acid
CAS No.	1360927-57-6
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	5-Methyl-1H-indazole-4-carboxylic acid; 4-Carboxy-5-methyl-1H-indazole; 5-Methyl-4-indazolecarboxylic acid; 1H-Indazole-4-carboxylic acid, 5-methyl-; 1360927-57-6; 5-Methylindazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-1H-Indazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.