Description

4-Cyano-2-Methyl-1H-Indole is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its functionalized indole scaffold, which serves as a critical precursor for the development of complex pharmacologically active molecules. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators that leverage the indole structure's biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to its electron-withdrawing cyano group.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents to study enzyme function.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for the synthesis of complex natural product analogs in university and CRO laboratories.

Basic Information

Product Name	4-Cyano-2-Methyl-1H-Indole
CAS No.	1360883-22-2
Molecular Formula	C10H8N2
Molecular Weight	156.19 g/mol
Synonyms	2-Methyl-1H-indole-4-carbonitrile; 2-Methyl-4-cyanoindole; 4-Cyano-2-methylindole; 1H-Indole-4-carbonitrile, 2-methyl-; 4-CN-2-Me-indole
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Methyl-1H-Indole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.