Description

1-(1-(tert-Butoxycarbonyl)Pyrrolidin-3-Yl)Pyrrolidine-3-Carboxylic Acid is a high-purity, bifunctional pyrrolidine derivative featuring a carboxylic acid group and a tert-butoxycarbonyl (Boc) protected amine. This compound is a critical building block in modern pharmaceutical research and development, valued for its versatility in constructing complex molecular architectures. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral scaffold for the synthesis of small molecule drug candidates targeting a range of therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce constrained pyrrolidine rings into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands in catalysis and chemical biology research.
• Boc-Protected Amine Building Block: The tert-butoxycarbonyl (Boc) protecting group allows for selective deprotection under mild acidic conditions, enabling sequential synthetic strategies.
• Chemical Library Development: Employed in parallel and combinatorial synthesis to generate diverse compound libraries for high-throughput screening.
• Academic Research: Utilized in universities and research institutes for methodological development and probe molecule synthesis.

Basic Information

Product Name	1-(1-(tert-Butoxycarbonyl)Pyrrolidin-3-Yl)Pyrrolidine-3-Carboxylic Acid
CAS No.	1360587-65-0
Molecular Formula	C14H24N2O4
Molecular Weight	284.35 g/mol
Synonyms	3-[3-(Boc-amino)pyrrolidin-1-yl]pyrrolidine-3-carboxylic acid; 1-[1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]pyrrolidine-3-carboxylic acid; 1-(1-Boc-pyrrolidin-3-yl)pyrrolidine-3-carboxylic acid; 3-(1-Boc-3-pyrrolidinyl)-3-pyrrolidinecarboxylic acid; 1-(1-(tert-Butoxycarbonyl)-3-pyrrolidinyl)-3-pyrrolidinecarboxylic acid; (1-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)pyrrolidin-3-yl)carboxylic acid; BOC-3-Pyrrolidineacetic acid, 1-(3-pyrrolidinyl)-; 1360587-65-0
EINECS	Contact for details

Quality Control

Our 1-(1-(tert-Butoxycarbonyl)Pyrrolidin-3-Yl)Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for use in pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.