Description

1-Bromo-8-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionalization, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the isoquinoline moiety.
• Ligand Synthesis: Employed in the preparation of novel chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable tool for medicinal chemistry and synthetic methodology research in university and corporate laboratories.

Basic Information

Product Name	1-Bromo-8-Chloroisoquinoline
CAS No.	1359828-80-0
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	8-Chloro-1-bromoisoquinoline; 1-Bromo-8-chloro-isoquinoline; Isoquinoline, 1-bromo-8-chloro-; 1359828-80-0; 8-Chloro-1-bromo-isoquinoline; 1-Bromo-8-chloroisoquinoline; 1-Bromo-8-chloro-2-azanaphthalene
EINECS	Contact for details

Quality Control

Our 1-Bromo-8-Chloroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.