Description

3-Cyclopropyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylic acid is a high-value, synthetically versatile heterocyclic building block. This compound is a critical intermediate in modern pharmaceutical research and development, prized for its unique fused indazole-cyclopropane scaffold. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small molecule drugs, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a core structure for designing new generation herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe Development: Used in medicinal chemistry to create tool compounds for target validation and pathway analysis.
• Material Science Precursor: Potential building block for advanced organic electronic materials and liquid crystals due to its rigid, planar structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and government labs for fundamental heterocyclic chemistry and methodology development.

Basic Information

Product Name	3-Cyclopropyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylic Acid
CAS No.	1359655-90-5
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	3-Cyclopropyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylic acid; 1H-Indazole-5-carboxylic acid, 4,5,6,7-tetrahydro-3-cyclopropyl-; 3-Cyclopropyl-1,4,5,6,7,8-hexahydroindazole-5-carboxylic acid; 5-Carboxy-3-cyclopropyl-4,5,6,7-tetrahydro-1H-indazole; 3-Cyclopropyl-4,5,6,7-tetrahydroindazole-5-carboxylic acid; 1359655-90-5; 3-Cyclopropyl-1,4,5,6,7,8-hexahydro-2H-indazole-5-carboxylic acid (tautomer).
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting critical parameters such as assay purity and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid functionality, keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.