Description

Spiro[Cyclopentane-1,3'-[3H]Indol]-2'(1'H)-One, 1'-(4-Piperidinyl)- is a high-purity, complex spirocyclic organic compound identified by CAS NO 1358667-60-3, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring fused indole and piperidine moieties, makes it a valuable building block for constructing novel pharmacologically active scaffolds. This compound is primarily utilized by research institutions and pharmaceutical development teams focused on discovering new therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Discovery: Serves as a core structure for developing potential modulators of neurological receptors and enzymes.
• Oncological Research: Employed in the design and synthesis of potential small-molecule inhibitors for cancer therapy.
• Chemical Biology Probes: Utilized to create specialized molecular probes for studying protein function and cellular signaling mechanisms.
• Process Chemistry Development: Acts as a critical intermediate during the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Spiro[Cyclopentane-1,3'-[3H]Indol]-2'(1'H)-One, 1'-(4-Piperidinyl)-
CAS No.	1358667-60-3
Molecular Formula	C16H20N2O
Molecular Weight	256.35 g/mol
Synonyms	1'-(4-Piperidinyl)spiro[cyclopentane-1,3'-[3H]indol]-2'(1'H)-one; 1-(Piperidin-4-yl)-1,3-dihydrospiro[indene-2,3'-pyrrolo[3,4-c]pyridin]-1'-one; Spiro[cyclopentane-1,3'-indole]-2'(1'H)-one, 1'-(4-piperidinyl)-; 1358667-60-3; 1'-(Piperidin-4-yl)-1'H-spiro[cyclopentane-1,3'-indol]-2'-one; 4-(2-Oxo-1'H-spiro[cyclopentane-1,3'-indol]-1'-yl)piperidine
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopentane-1,3'-[3H]Indol]-2'(1'H)-One, 1'-(4-Piperidinyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.