Description

1-Piperidinecarboxylic Acid, 4-(3-Ethyl-2,3-Dihydro-3-Methyl-2-Oxo-1H-Indol-1-Yl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. Pharmaceutical R&D teams and fine chemical manufacturers need it for developing next-generation therapeutic agents, where its precise stereochemistry and purity are paramount for successful clinical outcomes.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel drug candidates, especially for neurological and psychiatric applications.
• API Synthesis: Serves as a crucial building block in multi-step synthesis routes for complex target molecules in medicinal chemistry.
• Preclinical & Clinical Research: Used in the preparation of compounds for pharmacological screening, toxicity studies, and formulation development.
• Process Chemistry Development: Employed by process chemists to scale up and optimize synthetic pathways from laboratory to pilot plant and commercial production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the biopharma industry.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-(3-Ethyl-2,3-Dihydro-3-Methyl-2-Oxo-1H-Indol-1-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	1358667-45-4
Molecular Formula	C21H30N2O3
Molecular Weight	358.48 g/mol
Synonyms	tert-Butyl 4-(3-ethyl-3-methyl-2-oxoindolin-1-yl)piperidine-1-carboxylate; 1-Boc-4-(3-ethyl-3-methyl-2-oxo-2,3-dihydro-1H-indol-1-yl)piperidine; 4-(3-Ethyl-2,3-dihydro-3-methyl-2-oxo-1H-indol-1-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(1-Boc-4-piperidyl)-3-ethyl-3-methyl-indolin-2-one; BOC-Protected Indolinone Piperidine Derivative; CAS 1358667-45-4
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-(3-Ethyl-2,3-Dihydro-3-Methyl-2-Oxo-1H-Indol-1-Yl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.