Description

6-Bromo-4-Fluoro-1-Methyl-1H-Indazole is a high-purity, multi-functional heterocyclic building block of significant importance in modern organic synthesis. This compound is valued for its unique halogenated indazole core, which serves as a critical scaffold for constructing complex molecules with targeted biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the development of kinase inhibitors and other bioactive agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted cancer therapies and kinase inhibitors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its halogen-substituted indazole scaffold.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new generation herbicides and fungicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science: Potential intermediate for the development of advanced organic electronic materials and ligands for catalysis.

Basic Information

Product Name	6-Bromo-4-Fluoro-1-Methyl-1H-Indazole
CAS No.	1358574-94-3
Molecular Formula	C8H6BrFN2
Molecular Weight	229.05 g/mol
Synonyms	6-Bromo-4-fluoro-1-methylindazole; 1-Methyl-6-bromo-4-fluoro-1H-indazole; 6-Bromo-4-fluoro-1-methyl-1H-indazole; 1358574-94-3; 4-Fluoro-6-bromo-1-methylindazole; 1H-Indazole, 6-bromo-4-fluoro-1-methyl-
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-Fluoro-1-Methyl-1H-Indazole is produced and tested under strict quality management protocols to ensure consistency and high purity suitable for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.