Description

5-(Trifluoromethyl)-1-Methoxyisoquinoline is a high-value, fluorinated isoquinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a methoxy substituent, provides distinct electronic and steric properties essential for developing novel compounds with targeted functionalities. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to incorporate fluorine motifs to modulate the bioavailability, metabolic stability, and potency of their final products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, catalysts, or fluorinated organic frameworks with applications in catalysis and advanced materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	5-(Trifluoromethyl)-1-Methoxyisoquinoline
CAS No.	1357947-19-3
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	1-Methoxy-5-(trifluoromethyl)isoquinoline; 5-(Trifluoromethyl)-1-methoxy-isoquinoline; 1-Methoxyisoquinoline, 5-(trifluoromethyl)-; Isoquinoline, 1-methoxy-5-(trifluoromethyl)-; 1357947-19-3
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.