Description

7-(Trifluoromethyl)-3-Methoxyisoquinoline is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold, a methoxy substituent, and a highly electron-withdrawing trifluoromethyl group, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for creating functionalized organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probe: Utilized in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	7-(Trifluoromethyl)-3-Methoxyisoquinoline
CAS No.	1357947-03-5
Molecular Formula	C₁₁H₈F₃NO
Molecular Weight	227.18 g/mol
Synonyms	3-Methoxy-7-(trifluoromethyl)isoquinoline; 7-(Trifluoromethyl)-3-methoxy-isoquinoline; Isoquinoline, 3-methoxy-7-(trifluoromethyl)-; 1357947-03-5
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-3-Methoxyisoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.