Description

5-(Trifluoromethyl)Isoquinolin-3-Amine is a high-value, nitrogen-containing heterocyclic compound featuring a strategically positioned trifluoromethyl group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds. Its properties are leveraged in developing targeted therapies and high-performance specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Serves as a building block for creating new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Precursor: Used in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalytic systems and metal-organic frameworks (MOFs).
• Fluorine Chemistry Building Block: The trifluoromethyl group provides metabolic stability and lipophilicity, making it valuable for structure-activity relationship (SAR) studies.
• Chemical Biology Probe: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	5-(Trifluoromethyl)Isoquinolin-3-Amine
CAS No.	1357946-73-6
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	3-Amino-5-(trifluoromethyl)isoquinoline; 5-(Trifluoromethyl)-3-isoquinolinamine; 3-Isoquinolinamine, 5-(trifluoromethyl)-; 5-Trifluoromethylisoquinolin-3-ylamine; 1357946-73-6; 5-(Trifluoromethyl)isoquinolin-3-amine; 5-(Trifluoromethyl)-3-aminoisoquinoline
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including HPLC, NMR, and MS, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.