Description

Methyl 1-Chloroisoquinoline-6-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive chlorinated isoquinoline core, which serves as a key intermediate in constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by incorporating the isoquinoline scaffold into bioactive molecules.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for catalysis, and specialty polymers with unique optical or electronic properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research and assay development.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	Methyl 1-Chloroisoquinoline-6-Carboxylate
CAS No.	1357946-43-0
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	1-Chloro-6-(methoxycarbonyl)isoquinoline; Methyl 1-chloro-6-isoquinolinecarboxylate; 1-Chloroisoquinoline-6-carboxylic acid methyl ester; 6-(Methoxycarbonyl)-1-chloroisoquinoline; 1-Chloro-6-carbomethoxyisoquinoline; 1357946-43-0; Methyl 1-chloroisoquinoline-6-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-Chloroisoquinoline-6-Carboxylate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.