Description

6-(Trifluoromethyl)-1-Methoxyisoquinoline is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold, a methoxy substituent, and a highly electron-withdrawing trifluoromethyl group, which imparts distinct physicochemical properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• As a key pharmaceutical intermediate in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Utilized in agrochemical research for creating novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the fluorinated isoquinoline structure.
• Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Used in material science research for developing organic electronic materials or advanced ligands for catalysis.
• Acts as a precursor for the synthesis of more complex fluorinated heterocycles, which are valuable in various discovery chemistry programs.

Basic Information

Product Name	6-(Trifluoromethyl)-1-Methoxyisoquinoline
CAS No.	1357945-84-6
Molecular Formula	C₁₁H₈F₃NO
Molecular Weight	227.18 g/mol
Synonyms	1-Methoxy-6-(trifluoromethyl)isoquinoline; 6-(Trifluoromethyl)-1-methoxy-isoquinoline; 1-Methoxy-6-trifluoromethylisoquinoline; Isoquinoline, 1-methoxy-6-(trifluoromethyl)-; 1357945-84-6
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-1-Methoxyisoquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.