Description

6-(Trifluoromethyl)Isoquinolin-3-Amine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold and the electron-withdrawing trifluoromethyl group, which is instrumental in modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as ligands for catalysis or components in organic electronic devices.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	6-(Trifluoromethyl)Isoquinolin-3-Amine
CAS No.	1357945-70-0
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	3-Amino-6-(trifluoromethyl)isoquinoline; 6-(Trifluoromethyl)-3-isoquinolinamine; 6-Trifluoromethylisoquinolin-3-ylamine; 1357945-70-0; 6-(Trifluoromethyl)isoquinolin-3-amine; 3-Isoquinolinamine, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 6-(Trifluoromethyl)Isoquinolin-3-Amine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.