Description

6-(Trifluoromethyl)-3-Methoxyisoquinoline CAS NO 1357945-06-2 is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold with a trifluoromethyl group, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Acts as a precursor for developing specialty chemicals, such as ligands for catalysis or monomers for advanced polymers.
• Fluorine Chemistry Building Block: A valuable reagent for introducing the CF3-substituted isoquinoline moiety into more complex molecular architectures.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the synthesis of novel chemical libraries for screening.

Basic Information

Product Name	6-(Trifluoromethyl)-3-Methoxyisoquinoline
CAS No.	1357945-06-2
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	3-Methoxy-6-(trifluoromethyl)isoquinoline; 6-(Trifluoromethyl)-3-methoxy-isoquinoline; 1357945-06-2; 3-Methoxy-6-trifluoromethylisoquinoline; 6-Trifluoromethyl-3-methoxyisoquinoline; Isoquinoline, 6-(trifluoromethyl)-3-methoxy-
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-3-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.