Description

5-(Methylsulfonyl)-Indoline Hydrochloride is a high-purity organic compound featuring a sulfonyl-substituted indoline core. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides due to its unique sulfonyl-containing heterocyclic structure.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways in academic and industrial research settings.
• Material Science Applications: Potential intermediate for the synthesis of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	5-(Methylsulfonyl)-Indoline Hydrochloride
CAS No.	1357352-49-8
Molecular Formula	C9H11NO2S • HCl
Molecular Weight	249.71 g/mol
Synonyms	5-(Methanesulfonyl)-2,3-dihydro-1H-indole hydrochloride; Indoline, 5-(methylsulfonyl)-, hydrochloride; 1H-Indole, 2,3-dihydro-5-(methylsulfonyl)-, hydrochloride; 5-Methylsulfonylindoline HCl; 5-(Methylsulfonyl)indoline hydrochloride salt
EINECS	Contact for details

Quality Control

Our 5-(Methylsulfonyl)-Indoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.