Description

6-(4-Benzylpiperazin-1-Yl)Pyridine-3-Boronic Acid is a high-value boronic acid derivative and a key pharmaceutical intermediate. This compound is essential for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures critical in modern drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small molecule therapeutics, particularly for central nervous system (CNS) targets and kinase inhibitors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds between aryl/heteroaryl halides and boronic acids, a cornerstone reaction in medicinal chemistry.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Material Science Research: Potential precursor for constructing organic electronic materials and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in the discovery and synthesis of new crop protection agents.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	6-(4-Benzylpiperazin-1-Yl)Pyridine-3-Boronic Acid
CAS No.	1356242-29-9
Molecular Formula	C16H20BN3O2
Molecular Weight	297.16 g/mol
Synonyms	6-(4-Benzylpiperazin-1-yl)pyridine-3-boronic acid; 6-(4-Benzyl-1-piperazinyl)-3-pyridineboronic acid; 3-Pyridineboronic acid, 6-[4-(phenylmethyl)-1-piperazinyl]-; 6-(4-Benzylpiperazin-1-yl)pyridin-3-ylboronic acid; 6-(N-Benzylpiperazin-1-yl)nicotinoboronic acid; B-[6-(4-Benzyl-1-piperazinyl)-3-pyridinyl]boronic acid; 1356242-29-9
EINECS	Contact for details

Quality Control

Our 6-(4-Benzylpiperazin-1-Yl)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.