Description

(3Ar,4S,7R,7As)-3A,4,7,7A-Tetrahydro-4,7-Methano-1H-Isoindole-1,3(2H)-Dione is a high-purity, stereochemically defined bicyclic imide derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its rigid, fused-ring structure and defined stereochemistry make it invaluable for synthesizing complex molecules with specific three-dimensional architectures. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its complex bicyclic scaffold for novel modes of action.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Material Science Monomer: Potential use in creating specialized polymers with unique thermal and mechanical properties due to its rigid, fused-ring imide structure.
• Academic & R&D Laboratories: A valuable tool for synthetic organic chemists exploring new reaction methodologies and constructing complex natural product analogs.

Basic Information

Product Name	(3Ar,4S,7R,7As)-3A,4,7,7A-Tetrahydro-4,7-Methano-1H-Isoindole-1,3(2H)-Dione
CAS No.	1356221-52-7
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(3aR,4S,7R,7aS)-3a,4,7,7a-Tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione; endo-Norborn-5-ene-2,3-dicarboximide; endo-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid imide; endo-Norbornene dicarboximide; (1S,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboximide; endo-NBDI; endo-Norborn-5-ene-cis-2,3-dicarboximide
EINECS	Contact for details

Quality Control

Our (3Ar,4S,7R,7As)-3A,4,7,7A-Tetrahydro-4,7-Methano-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity verification by HPLC, to support your critical R&D and scale-up activities. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.