Description

n-(Acetyl-D3)-S-(1-Cyano-2-Hydroxyethyl)Cysteine Dicyclohexylamine Salt is a high-purity, deuterated biochemical reagent designed for advanced research and development. This compound is critical for applications requiring precise isotopic labeling, such as in metabolic pathway tracing and quantitative mass spectrometry analysis. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on proteomics, biomarker discovery, and drug metabolism studies.

Application

• Isotopic Internal Standard for LC-MS/MS: Serves as a critical quantitative standard in bioanalytical method development for accurate pharmacokinetic and metabolomic studies.
• Proteomics Research: Used in the study of protein modifications, specifically for tracing and quantifying cysteine-related adducts or modifications in complex biological samples.
• Metabolic Pathway Analysis: Employed as a deuterium-labeled tracer to investigate sulfur-containing amino acid metabolism and related biochemical pathways.
• Pharmaceutical Impurity Profiling: Acts as a reference standard for identifying and characterizing process-related impurities or degradation products in drug substances.
• Biomarker Discovery and Validation: Facilitates the accurate detection and quantification of low-abundance metabolites in clinical and preclinical samples.
• Stable Isotope Labeling in Cell Culture (SILAC): Can be incorporated into advanced labeling strategies for comparative proteomic analysis.

Basic Information

Product Name	n-(Acetyl-D3)-S-(1-Cyano-2-Hydroxyethyl)Cysteine Dicyclohexylamine Salt
CAS No.	1356017-48-5
Molecular Formula	C19H32D3N3O4S
Molecular Weight	~398.6 g/mol
Synonyms	N-Acetyl-D3-S-(1-cyano-2-hydroxyethyl)cysteine dicyclohexylamine salt; Deuterated N-Acetyl-S-(1-cyano-2-hydroxyethyl)cysteine DCHA salt; (2R)-2-Acetamido-3-[[(2R)-1-cyano-2-hydroxyethyl]sulfanyl]propanoic acid-d3 compound with dicyclohexylamine; N-Acetyl-3-deuterio-S-(1-cyano-2-hydroxyethyl)-L-cysteine dicyclohexylammonium salt; ACE-D3 DCHA Salt; A deuterated analog of N-Acetyl-S-(1-cyano-2-hydroxyethyl)cysteine
EINECS	Contact for details

Quality Control

Every batch of n-(Acetyl-D3)-S-(1-Cyano-2-Hydroxyethyl)Cysteine Dicyclohexylamine Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment. Our quality assurance protocol is designed to meet the stringent requirements of research and regulatory standards. Certificates of Analysis (COA) detailing batch-specific results for purity, isotopic purity (D-content), and impurities are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and desiccated after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.