Description

1-[6-(3,4-Dihydro-1H-Isoquinolin-2-Yl)-5-Methyl-Pyridin-3-Yl]-Propan-1-One is a high-purity, advanced pharmaceutical intermediate belonging to a class of nitrogen-containing heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. Pharmaceutical research and development organizations, as well as fine chemical manufacturers, require this material for its precise molecular architecture to enable efficient and scalable synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in neurological and psychiatric therapeutic research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds via further functionalization.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships.
• Process Chemistry: Serves in the development and optimization of scalable manufacturing processes for target APIs.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API production.

Basic Information

Product Name	1-[6-(3,4-Dihydro-1H-Isoquinolin-2-Yl)-5-Methyl-Pyridin-3-Yl]-Propan-1-One
CAS No.	1355189-78-4
Molecular Formula	C18H20N2O
Molecular Weight	280.37 g/mol
Synonyms	1-[6-(3,4-Dihydro-1H-isoquinolin-2-yl)-5-methylpyridin-3-yl]propan-1-one; 1-Propanone, 1-[6-(3,4-dihydro-1H-isoquinolin-2-yl)-5-methyl-3-pyridinyl]-; 5-Methyl-6-(1,2,3,4-tetrahydroisoquinolin-2-yl)nicotinophenone; 2-[5-(1-Oxopropyl)-3-methyl-2-pyridyl]-1,2,3,4-tetrahydroisoquinoline; 1355189-78-4
EINECS	Contact for details

Quality Control

Our 1-[6-(3,4-Dihydro-1H-Isoquinolin-2-Yl)-5-Methyl-Pyridin-3-Yl]-Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.