Description

4,5,6,7-Tetrahydro-1H-Indazole-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1354950-72-3. This compound is a critical building block in modern medicinal chemistry, valued for its indazole core which is a privileged scaffold in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) and inflammatory targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Scaffold: Serves as a core structural element for creating libraries of compounds targeting kinases and other enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of candidate drugs.
• Biochemical Tool Compound: Employed in vitro to study biological pathways and protein-ligand interactions.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value molecules for clinical trials.

Basic Information

Product Name	4,5,6,7-Tetrahydro-1H-Indazole-6-Carboxylic Acid
CAS No.	1354950-72-3
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	6-Carboxy-4,5,6,7-tetrahydro-1H-indazole; 1H-Indazole-6-carboxylic acid, 4,5,6,7-tetrahydro-; Tetrahydroindazole-6-carboxylic acid; 4,5,6,7-Tetrahydroindazole-6-carboxylic acid; 6-Carboxy-4,5,6,7-tetrahydroindazole; 1354950-72-3; 4,5,6,7-Tetrahydro-1H-indazol-6-ylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydro-1H-Indazole-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.