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N1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine CAS NO 1354911-17-3


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CAS No.:1354911-17-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine is a high-value, organoboron-containing diamine building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular construction, particularly in the development of complex pharmaceutical intermediates and functional materials. Its primary utility lies in Suzuki-Miyaura cross-coupling reactions, where the boronate ester group enables efficient carbon-carbon bond formation under mild conditions.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
  • Agrochemical Research: Building block for developing novel crop protection agents and herbicides with specific modes of action.
  • Material Science: Used in the creation of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
  • Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and sensors.
  • Academic & R&D Laboratories: Essential reagent for methodological development in organic synthesis and catalysis studies.
  • Ligand Synthesis: Precursor for creating novel chelating ligands used in homogeneous catalysis and metal complexation.

Basic Information

Product Name N1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine
CAS No. 1354911-17-3
Molecular Formula C14H24BN3O2
Molecular Weight 277.17 g/mol
Synonyms 2-[(2-Aminoethyl)amino]-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; N1-(4-Methyl-5-(Pinacolatoboryl)Pyridin-2-Yl)Ethylenediamine; 5-(Pinacolatoboryl)-4-methyl-2-((2-aminoethyl)amino)pyridine; 2-((2-Aminoethyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-picoline; Ethane-1,2-diamine, N1-[4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; CAS 1354911-17-3; Boronic ester pyridine diamine derivative
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Quality Control

Our N1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity building blocks for research and cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C. The compound is moisture-sensitive; keep the container tightly sealed to minimize exposure to humidity.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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