Description

Methyl 7-Bromo-1H-Benzodiazole-5-Carboxylate CAS NO 1354756-19-6 is a high-purity brominated benzimidazole derivative, a crucial advanced pharmaceutical intermediate (API) and building block in organic synthesis. Its value lies in its functionalized structure, which enables the construction of complex molecules for drug discovery and material science. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for potential antiviral, anticancer, or CNS-targeting drugs.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the benzimidazole core into more complex molecular architectures.
• Agrochemical Research: Serves as a starting material for developing new fungicides or herbicides due to the bioactive benzimidazole scaffold.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Acts as a versatile scaffold for creating molecular probes to study enzyme function or cellular pathways.

Basic Information

Product Name	Methyl 7-Bromo-1H-Benzodiazole-5-Carboxylate
CAS No.	1354756-19-6
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	7-Bromo-1H-benzimidazole-5-carboxylic acid methyl ester; Methyl 7-bromo-1H-benzimidazole-5-carboxylate; 1H-Benzimidazole-5-carboxylic acid, 7-bromo-, methyl ester; 7-Bromo-1H-benzo[d]imidazole-5-carboxylic acid methyl ester; 1354756-19-6; Methyl 7-bromobenzimidazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 7-Bromo-1H-Benzodiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.