Description

(S)-3-(2,4-Dichloro-Phenylsulfanyl)-Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used as a precursor in the development of advanced pesticides and herbicides, leveraging its dichlorophenyl moiety.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes to study enzyme function and receptor interactions.
• Process Chemistry & Scale-Up: Supplied in bulk quantities for pilot plant and commercial manufacturing of target molecules.
• Custom Synthesis & Contract Manufacturing: A critical component for companies offering bespoke chemical synthesis services.

Basic Information

Product Name	(S)-3-(2,4-Dichloro-Phenylsulfanyl)-Pyrrolidine Hydrochloride
CAS No.	1354000-39-7
Molecular Formula	C10H11Cl3NS
Molecular Weight	291.62 g/mol
Synonyms	(S)-3-((2,4-Dichlorophenyl)thio)pyrrolidine hydrochloride; (3S)-3-[(2,4-Dichlorophenyl)sulfanyl]pyrrolidine hydrochloride; (S)-3-(2,4-Dichlorobenzenesulfanyl)pyrrolidine HCl; Pyrrolidine, 3-[(2,4-dichlorophenyl)thio]-, hydrochloride, (3S)-; (S)-3-(2,4-Dichloro-phenylsulfanyl)-pyrrolidine HCl
EINECS	Contact for details

Quality Control

Our production of (S)-3-(2,4-Dichloro-Phenylsulfanyl)-Pyrrolidine Hydrochloride adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.