Description

3-Methyl-Thiophene-2-Carboxylic Acid Piperidin-3-Ylamide Hydrochloride is a high-purity, non-racemic chiral building block of significant interest in advanced pharmaceutical research and development. Its complex heterocyclic structure, featuring both thiophene and piperidine motifs, makes it a valuable intermediate for constructing novel bioactive molecules. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of potential drug candidates, particularly those targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry: Serves as a building block in the scale-up and route development for potential therapeutic compounds.
• Biochemical Research: Employed as a ligand or probe in the study of biological targets and enzyme interactions.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	3-Methyl-Thiophene-2-Carboxylic Acid Piperidin-3-Ylamide Hydrochloride
CAS No.	1353987-25-3
Molecular Formula	C12H17ClN2OS
Molecular Weight	272.79 g/mol
Synonyms	3-Methylthiophene-2-carboxylic acid (3-piperidinyl)amide hydrochloride; (R/S)-3-Methyl-N-(piperidin-3-yl)thiophene-2-carboxamide hydrochloride; 3-Methylthiophene-2-carboxamide, N-3-piperidinyl-, hydrochloride; Piperidin-3-yl 3-methylthiophene-2-carboxamide hydrochloride; 1353987-25-3; 3-Methyl-thiophene-2-carboxylic acid piperidin-3-ylamide HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-Thiophene-2-Carboxylic Acid Piperidin-3-Ylamide Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting regulatory filings for research and development. A detailed Certificate of Analysis (COA) including chiral purity, assay, and impurity profiles is supplied with each shipment to guarantee it meets your specific research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.