Description

3-Methyl-Thiophene-2-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical of significant synthetic utility. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and other therapeutic areas. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in process development and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry Development: Serves as a key starting material (KSM) or intermediate in the development and optimization of scalable commercial manufacturing routes for APIs.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke molecules for client projects.

Basic Information

Product Name	3-Methyl-Thiophene-2-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride
CAS No.	1353985-79-1
Molecular Formula	C13H21ClN2OS
Molecular Weight	288.84 g/mol
Synonyms	N-Methyl-N-(piperidin-4-yl)-3-methylthiophene-2-carboxamide hydrochloride; 3-Methylthiophene-2-carboxylic acid methyl-piperidin-4-yl-amide HCl; Methyl-piperidin-4-yl-amide of 3-methyl-2-thiophenecarboxylic acid hydrochloride; 2-Thiophenecarboxamide, N-methyl-N-(4-piperidinyl)-3-methyl-, hydrochloride; 1353985-79-1; 3-Methyl-thiophene-2-carboxylic acid methyl-piperidin-4-yl-amide HCl salt
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-Thiophene-2-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with each batch, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.