Description

3-Methyl-Thiophene-2-Carboxylic Acid Methyl-Piperidin-3-Yl-Amide Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Chemical Library Synthesis: Employed in the creation of diverse compound libraries for high-throughput screening (HTS) against biological targets.
• Process Chemistry: Used in route scouting and scale-up studies for the development of efficient and cost-effective manufacturing processes.

Basic Information

Product Name	3-Methyl-Thiophene-2-Carboxylic Acid Methyl-Piperidin-3-Yl-Amide Hydrochloride
CAS No.	1353981-59-5
Molecular Formula	C13H21ClN2OS
Molecular Weight	288.84 g/mol
Synonyms	3-Methylthiophene-2-carboxylic acid methyl(piperidin-3-yl)amide hydrochloride; Methyl(3-piperidinyl)[(3-methyl-2-thienyl)carbonyl]amine hydrochloride; N-Methyl-N-(piperidin-3-yl)-3-methylthiophene-2-carboxamide hydrochloride; 3-Methyl-N-methyl-N-(3-piperidinyl)-2-thiophenecarboxamide hydrochloride; 1353981-59-5
EINECS	Contact for details

Quality Control

Our 3-Methyl-Thiophene-2-Carboxylic Acid Methyl-Piperidin-3-Yl-Amide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identification, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.