Description

Thiophene-2-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to improve drug efficacy and selectivity.
• API Development: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes for biological target identification and validation in drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Thiophene-2-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride
CAS No.	1353962-93-2
Molecular Formula	C12H17ClN2OS
Molecular Weight	272.79 g/mol
Synonyms	N-Methyl-N-(piperidin-4-yl)thiophene-2-carboxamide hydrochloride; 2-Thiophenecarboxamide, N-methyl-N-4-piperidinyl-, hydrochloride; Methyl-piperidin-4-yl-amide of Thiophene-2-carboxylic Acid Hydrochloride; T2CA-MPA HCl; 1353962-93-2; UNII-9F6J2S3Q4F; 9F6J2S3Q4F
EINECS	Contact for details

Quality Control

Our Thiophene-2-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.