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(1R)-3,3'-Bis[3,5-Bis(1,1-Dimethylethyl)-4-Methoxyphenyl]-[1,1'-Binaphthalene]-2,2'-Diol CAS NO 1353682-93-5


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CAS No.:1353682-93-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R)-3,3'-Bis[3,5-Bis(1,1-Dimethylethyl)-4-Methoxyphenyl]-[1,1'-Binaphthalene]-2,2'-Diol is a sophisticated chiral binaphthol derivative, a high-value specialty chemical prized for its unique sterically hindered and electron-rich molecular architecture. Its primary value lies in its exceptional performance as a chiral ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure compounds. This compound is essential for advanced research and manufacturing in pharmaceuticals, agrochemicals, and materials science, where precise stereochemical control is paramount.

Application

  • Asymmetric Catalysis: Serves as a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
  • Pharmaceutical Intermediate Synthesis: Critical for the enantioselective synthesis of active pharmaceutical ingredients (APIs) requiring high optical purity.
  • Agrochemical Development: Used in the research and production of chiral pesticides and herbicides with enhanced efficacy and selectivity.
  • Advanced Material Science: A key building block for chiral polymers, liquid crystals, and molecular recognition systems.
  • Organic Synthesis Research: A versatile tool for academic and industrial R&D laboratories exploring novel stereoselective transformations.
  • Chiral Resolution Agent: Can be utilized in the separation of racemic mixtures into their individual enantiomers.

Basic Information

Product Name (1R)-3,3'-Bis[3,5-Bis(1,1-Dimethylethyl)-4-Methoxyphenyl]-[1,1'-Binaphthalene]-2,2'-Diol
CAS No. 1353682-93-5
Molecular Formula C56H64O4
Molecular Weight 801.11 g/mol
Synonyms (R)-3,3'-Bis(3,5-di-tert-butyl-4-methoxyphenyl)-1,1'-bi-2-naphthol; (R)-3,3'-Bis(3,5-di-tert-butyl-4-methoxyphenyl)-BINOL; (R)-DTB-MeO-BINOL; (R)-3,3'-Bis(3,5-di-tert-butyl-4-methoxyphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Bis(3,5-di-tert-butyl-4-anisyl)-BINOL; (R)-3,3'-Bis(3,5-di-tert-butyl-4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol; (R)-3,3'-Bis(3,5-di-tert-butyl-4-hydroxyphenyl methyl ether)-BINOL; Chiral DTB-MeO-BINOL Ligand
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Quality Control

Our (1R)-3,3'-Bis[3,5-Bis(1,1-Dimethylethyl)-4-Methoxyphenyl]-[1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for demanding catalytic applications. Comprehensive Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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