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n-(3-tert-Butyl-1-Methyl-1H-Pyrazol-5-Yl)-4-(3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Phenyl)Thiazol-2-Amine CAS NO 1353570-20-3


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CAS No.:1353570-20-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(3-tert-Butyl-1-Methyl-1H-Pyrazol-5-Yl)-4-(3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Phenyl)Thiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted small-molecule drugs.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
  • Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of protein kinase inhibitors.
  • Biochemical Research: Utilized as a reference standard or probe in biochemical assays and target validation studies.
  • Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name n-(3-tert-Butyl-1-Methyl-1H-Pyrazol-5-Yl)-4-(3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Phenyl)Thiazol-2-Amine
CAS No. 1353570-20-3
Molecular Formula C22H26N6OS
Molecular Weight 422.55 g/mol
Synonyms 4-(3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-N-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)thiazol-2-amine; 2-Thiazolamine, N-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-; UNII-9G0C8U3G8F; 1353570-20-3; CHEMBL3186302; BDBM50157857; AKOS009158932; ZINC000004169756
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Quality Control

Our n-(3-tert-Butyl-1-Methyl-1H-Pyrazol-5-Yl)-4-(3-Methoxy-4-(4-Methyl-1H-Imidazol-1-Yl)Phenyl)Thiazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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