Description

7-(Trifluoromethyl)-1-Methoxyisoquinoline CAS NO 1352934-60-1 is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold, a methoxy group, and a trifluoromethyl substituent, which is highly sought after for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Acts as a building block for creating advanced organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies due to its distinct fluorine signature.
• Fluorine Chemistry: A valuable substrate for further functionalization via cross-coupling reactions, leveraging the reactive sites on the isoquinoline ring.

Basic Information

Item	Details
Product Name	7-(Trifluoromethyl)-1-Methoxyisoquinoline
CAS No.	1352934-60-1
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	1-Methoxy-7-(trifluoromethyl)isoquinoline; 7-(Trifluoromethyl)-1-methoxy-isoquinoline; 1-Methoxy-7-trifluoromethylisoquinoline; Isoquinoline, 1-methoxy-7-(trifluoromethyl)-; 1352934-60-1
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.