Description

Ethyl 4-Fluoro-7-Methyl-1H-Indole-2-Carboxylate is a high-purity, fluorinated indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, leveraging the biological activity of the fluorinated indole scaffold.
• Material Science Research: Serves as a precursor for functionalized organic materials and advanced polymers with specific electronic or photonic properties.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up processes.

Basic Information

Product Name	Ethyl 4-Fluoro-7-Methyl-1H-Indole-2-Carboxylate
CAS No.	1352906-36-5
Molecular Formula	C₁₂H₁₂FNO₂
Molecular Weight	221.23 g/mol
Synonyms	4-Fluoro-7-methyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4-fluoro-7-methylindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 4-fluoro-7-methyl-, ethyl ester; 4-Fluoro-7-methylindole-2-carboxylic acid ethyl ester; 1352906-36-5; Ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-7-Methyl-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.