Description

Methyl 5-Methyl-3-(2,2,2-Trifluoro-Acetylamino)-Thiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular architecture in the development of novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical industries as a key intermediate for creating complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Research: Serves as a key precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene and trifluoroacetyl motifs for enhanced bioactivity.
• Material Science: Used in the research and development of specialty polymers, organic semiconductors, and advanced materials where the thiophene core contributes to electronic properties.
• Chemical Synthesis: Acts as a versatile synthon for organic chemists, enabling the construction of complex heterocyclic frameworks through further functionalization of the ester and amide groups.
• Academic & R&D: An essential reagent for universities and contract research organizations (CROs) exploring new chemical spaces and reaction methodologies in medicinal and synthetic chemistry.

Basic Information

Product Name	Methyl 5-Methyl-3-(2,2,2-Trifluoro-Acetylamino)-Thiophene-2-Carboxylate
CAS No.	1352723-61-5
Molecular Formula	C10H10F3NO3S
Molecular Weight	281.25 g/mol
Synonyms	Methyl 3-[(2,2,2-trifluoroacetyl)amino]-5-methylthiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[(2,2,2-trifluoroacetyl)amino]-5-methyl-, methyl ester; 5-Methyl-3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylic acid methyl ester; 3-(Trifluoroacetylamino)-5-methylthiophene-2-carboxylic acid methyl ester; Methyl 5-methyl-3-(trifluoroacetylamino)thiophene-2-carboxylate; CAS 1352723-61-5
EINECS	Contact for details

Quality Control

Our Methyl 5-Methyl-3-(2,2,2-Trifluoro-Acetylamino)-Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.